Heart failure is a medical condition
caused due to abnormal cardiac structure and function. Heart failure is a
chronic progressive disorder that affects blood pumping capacity of the
heart muscles, leading to insufficient supply of blood to the whole
body. Systolic heart failure and diastolic heart failure are the two
main types of heart failure. In systolic heart failure, the left
ventricle of the heart fails to contract normally, while in diastolic
heart failure, the muscles in the left ventricle become stiff. Common
symptoms of heart failure include fatigue, swelling at the ankles, feet,
and legs, weight gain, and increased urge to urinate. Heart failure has
significant burden on the global health care system, affecting more
than 26 million people across the globe. It is estimated that heart
failure across the globe had cost around US$ 100 Bn in 2012.
The global heart failure therapeutics
market is estimated to be primarily driven by high incidence rate of
heart failure disorders across the globe. Around 5 million Americans are
estimated to be currently living with congestive heart failure and more
than 5.5 million new cases are diagnosed every year in the U.S. Also,
heart failure cases account for 11 million visits to physicians every
year in the U.S. and higher number of hospitalization than that of all
forms of cancer combined together. Moreover, adoption of western
lifestyle, lack of physical exercise, daily life stress, unhealthy diet,
and high prevalence of obesity are the key causes leading to heart
failure. These factors are projected to fuel the growth of the global
heart failure therapeutics market during the forecast period. Rise in
trend of new product development and commercialization among the leading
players operating in the global market has been observed since the past
few years. Increase in demand and easy availability of heart failure
therapeutics drugs are estimated to drive the growth of the market
during the forecast period.
The global heart failure therapeutics
market can be segmented based on heart failure stage, drug class,
distribution channel, and region. In terms of heart failure stage, the
market can be classified into class I, Class II, Class III, and Class
IV. Based on drug class, the market can be divided into
Angiotensin-Converting Enzyme Inhibitors, Angiotensin Receptor Blockers,
Diuretics, Beta Blockers, Procoralan, Mineralocorticoid Receptor
Antagonists, and others. Angiotensin-converting enzyme (ACE) inhibitors
are a group of medication used for dilation or widening of heart blood
vessels to facilitate the free flow of blood to the heart and to lower
the blood pressure. Most commonly used ACE inhibitors include Accupril,
Aceon, Altace, Capoten, Lotensin, Mavik and Monopril. ACE inhibitors are
generally prescribed for management of high blood pressure, heart
failure, coronary artery diseases, diabetes, and other cardiovascular
disorders. The ACE inhibitors segment is projected to dominate global
heart failure treatment market by the end of 2026, expanding at a
significant CAGR during the forecast period. In terms of distribution
channel, the market can be segmented into hospital pharmacy, retail
pharmacy, and online pharmacy. The hospital pharmacy segment is poised
to hold prominent share of the market by the end of 2026.
In terms of region, the global heart
failure therapeutics market can be split into North America, Europe,
Asia Pacific, Latin America, and Middle East & Africa. North America
and Europe are estimated to account for a dominant share of the global
market, owing to high prevalence and rise in incidence rate of heart
failure, large base of pharmaceutical companies, high awareness level,
well-established health care facilities, and favorable medical
reimbursement policies in these regions. Moreover, rapidly increasing
geriatric population which is more prone to suffer from heart failure in
countries such as the U.S., the U.K., Germany, and France is likely to
contribute to major market share of these regions by the end of 2026.
The heart failure therapeutics market in Asia Pacific is projected to
grow rapidly during the forecast period, owing to large pool of patients
affected with heart failure in highly populous countries such as India
and China, large base of geriatric population in Japan, and rapidly
changing health care sector in the emerging countries. Increase in per
capita health care expenditure, rapidly growing biopharmaceutical
industry, and various initiatives taken by the government in the
emerging countries to promote health care are estimated to fuel the
growth of the heart failure therapeutics market in Asia Pacific during
the forecast period. The heart failure therapeutics market in Latin
America and Middle East & Africa is projected to grow at a moderate
rate during the forecast period.
The global heart failure therapeutics
market is highly fragmented. A large number of manufacturers holds
prominent market share in respective regions. A key trend of mergers and
acquisitions and new product development among the leading players has
been observed since the past few years. Companies are engaging in
mergers and acquisitions in to order to strengthen their product
portfolio and enhance their geographic presence in respective regions.
Key players operating in the global heart failure therapeutics market
include Amgen Inc., Pfizer Inc., Johnson & Johnson, Novartis AG,
Bristol-Myers Squibb Company, Abbott, Bayer AG, Orion Corporation, Merck
& Co. Inc., and Cardiorentis Ag.
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