Scaffolds are artificial extracellular
matrices that support 3D tissue regenerations and accommodate cells.
These can be temporary or permanent matrices which provide chemical,
mechanical, and biological support for tissue formation. Scaffold
technology is employed to perform 3D culture assays that include cell to
cell interactions, high throughput screening, cell to matrix
interactions, transfections, and cell migration assays. Growing
regenerative technology has been attributed to the growth of the
scaffold technology market which has led to the development of
bio-scaffolds. Scaffolds act as a template for tissue formation, which
are subject to biophysical stimuli through a bioreactor, a system which
applies chemical and mechanical stimuli to the cells; or are provided
with growth factors.
In terms of material, the scaffold
technology market can be segmented into bio-inert, bioresorbable, and
bioactive. Based on technology, the market can be segmented into
nanofiber-based scaffolds, polymeric scaffolds, hydrogels, and
micro-patterned surface microplates. In terms of application, the
scaffold technology market can be segmented into drug development,
tissue culture, cancer treatment, stem cell research, and regenerative
technology. End-users in the scaffold technology market include
biotechnology and pharmaceutical organizations, research laboratories,
hospitals, and diagnostic laboratories. In terms of region, the market
can be segmented into North America, Latin America, Asia Pacific,
Europe, and Middle East & Africa.
Scaffold technology provides
opportunities to address the challenges associated with tissue culture
such as vascularization and enable organ implant regeneration employed
in the treatment of damaged and diseased organs or tissues. Increasing
number of applications would contribute to the growth of scaffold
technology market. In addition, rising accidents leading to organ damage
and increase in geriatric population that add to the rising number of
people with non-functioning of organs contribute to the growth of the
scaffold technology market. In addition, ongoing research on designing
matrix-based 3D substrates that enable interaction between implants and
host microenvironment for optimal functioning of the implanted cells and
drug release is expected to boost the market in terms of revenue during
the forecast period. However, the emergence of scaffold-free technology
for cell culturing is expected to hamper the scaffold technology market
during the forecast period.
Hydrogels based scaffolds are expected to
dominate the scaffold technology market due to the continuous progress
in their development. However, nanofiber-based scaffolds are expected to
record highest growth rate during the forecast period, owing to the
growing nanotechnology and their ability to mimic nanoscale properties.
Growing investments by biotechnology companies for the development of
products related to scaffold technology is expected to contribute to the
growth of the scaffold technology market.
North America is expected to dominate the
scaffold technology market. Growth of the market in the region can be
attributed to well-developed infrastructure in the region, ongoing
research, and the presence of major market players in the region.
However, the scaffold technology market in Asia Pacific is expected to
record the highest growth rate during the forecast period, owing to the
increasing government focus on boosting research and development in the
pharmaceutical industry and the improving health care infrastructure in
the region.
Leading players in the scaffold
technology market include 3D Biomatrix, 3D Biotek LLC, Acelity (LifeCell
Corporation), Avacta Life Sciences Limited, Becton, Dickinson and
Company, Medtronic (Covidien plc), Merck KGaA (Sigma-Aldrich Co. LLC),
Molecular Matrix, Inc., Molecular Partners, Nanofiber Solutions,
NuVasive, Inc., Pelo Biotech GmbH, ReproCELL Europe Ltd. (Reinnervate),
Thermo Fisher Scientific, Inc., Vericel Corporation, and Xanofi. The
leading players in the market have been focusing on diversifying their
product portfolios and expanding their distribution networks to
strengthen their market position.
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