Antidepressants are drugs used for the
treatment of depressive disorders including dysthymia, obsessive
compulsive disorder, anxiety, chronic pain, eating disorders, and
neuropathic pain. Depression is a medical disorder which is related to
the brain. Symptoms of depression include feeling sad and tired, lacking
energy, and having difficulty enjoying routine daily activities.
According to CDC, depression affects about 1 in every 5 individuals in
the U.S. According to WHO (World Health Organization), at present an
estimated 350 million people worldwide are affected by depression.
Depression affects 10% to 15% men and about 10% to 25% of women.
The antidepressants market has been
segmented based on the drug classes commonly used for the treatment of
various types of depressive disorders. There are different types of
antidepressant drugs available in the market such as selective serotonin
reuptake inhibitors (SSRI), serotonin and noradrenaline reuptake
inhibitors (SNRI), noradrenaline reuptake inhibitors, tricyclic
antidepressants (TCA), reversible inhibitors of monoamine oxidase A
(RIMA), tetracyclic antidepressants, etc. The different types of
antidepressants are used in the treatment of depressive disorders. The
different classes of antidepressants are as effective as each other, but
some patients respond better to one antidepressant compared to another
antidepressant. Side effects can also be different between these groups
of antidepressants. Different types of depression disorders include
dysthymic disorder, postpartum depression, psychotic depression, major
or clinical depressive disorder, and seasonal affective disorder.
Factors driving the antidepressants
market are declining side effects and rising efficacy of drugs in
various classes as well as growing geriatric population where rate of
mental illness is higher. However, the overall antidepressants market
growth would decrease due to patent expiry of key antidepressants,
fragile pipeline of new drugs, increasing number of generic drug
alternatives, and growing prevalence of treatment-resistant psychiatric
disorders.
Region wise, the global fermented
ingredients market is segmented into five regions; North America,
Europe, Asia Pacific, Latin America, and the Middle East & Africa.
North America is the most dominant market for antidepressants due to the
presence of a large patient population suffering from various types of
anxiety disorders and depression. However, the antidepressants market in
the U.S. is currently saturated, as several antidepressant drugs are
available on prescription for the same indication. Hence, the future
growth of the market would depend on introduction of efficacious drugs
for new indications. Moreover, loss of patent exclusivity, market
maturity, generic infiltration, and shortened drug lifecycles are the
additional factors that contribute to the decline in market growth in
the region. Asia Pacific is expected to witness appreciable growth due
to multiple factors such as high prevalence of psychiatric disorders and
rapid economic growth in countries such as China, Japan, and Australia.
Additionally, positive marketing approval for innovative medicines is
likely to drive the market in the near future.
Currently, the market is highly
fragmented and competitive in nature due to the involvement of both
large and small pharmaceutical companies. AstraZeneca plc, Eli Lilly and
Company, Forest Laboratories, GlaxoSmithKline plc, H. Lundbeck A/S,
Johnson & Johnson, Merck & Co., Inc., Pfizer, Inc. and Sanofi
S.A. are major companies operating in the antidepressants market.
Majority of the market players are focusing on expanding distribution
network as well as expanding geographical presence, as Asia Pacific, the
Middle East& Africa, and Latin America are developing regions with
an increasing prevalence of various types of depressive disorders and
improving economic conditions. Differences in clinical efficacy between
drugs are generally small because most modern antidepressants work
through a common biological mechanism. As a result, drug makers use
direct-to-consumer advertising and tweak side effect profiles in order
to differentiate their products.
The report offers a comprehensive
evaluation of the market. It does so via in-depth qualitative insights,
historical data, and verifiable projections about market size. The
projections featured in the report have been derived using proven
research methodologies and assumptions. By doing so, the research report
serves as a repository of analysis and information for every facet of
the market, including but not limited to: Regional markets, technology,
types, and applications.
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