Global Intravenous Immunoglobulin Market – Snapshot
Immunoglobulins are highly purified,
sterile specific medical therapy solutions containing gammaglobulin G
(IgG) in a concentration of 95% or more. These are manufactured from
highly refined pool of human plasma collected from at least 100 donors
or more. Immunoglobulins can be administered through three different
routes: intramuscular, intravenous, and subcutaneous. Intramuscular
route of administration is a relatively older method and is not
preferred currently, as it is painful. Intravenous immunoglobulin has
emerged as a boon in the last few decades for patients with compromised
immune system.
The global intravenous immunoglobulin
market continues to expand at a high growth rate. The market is driven
by rise in global prevalence of autoimmune diseases such as primary
humoral immunodeficiency (PIDD), multiple sclerosis, immune
thrombocytopenia purpura (ITP), autoimmune hemolytic anemia, and
Kawasaki syndrome. The global intravenous immunoglobulin market is
projected to witness significant growth in the next few years due to
technological advancements leading to development of new production and
purification methods. Rapid increase in the number of neurological
disorders, rise in the global geriatric population, and ever-increasing
number of patients across the world have fueled demand for quick and
reliable treatment measures. These factors have also driven usage of
intravenous immunoglobulin for the treatment of off-label indications.
Moreover, increase in investments in research and development of novel
products by private and government bodies is likely to propel the market
in the near future.
The global intravenous immunoglobulin
market has been segmented based on indication, end-user, and region. In
terms of indication, the market has been classified into chronic
inflammatory demyelinating polyneuropathy (CIDP), primary humoral
immunodeficiency, idiopathic thrombocytopenic purpura (ITP),
Guillain-Barre syndrome, myasthenia gravis, multifocal motor neuropathy
(MMN), Kawasaki disease, hypogammaglobulinemia, chronic lymphocytic
leukemia, and others. Based on end-user, the global intravenous
immunoglobulin market has been divided into hospitals, clinics, and home
care. In terms of region, the global market has been segmented into
North America, Europe, Asia Pacific, Latin America, and Middle East
& Africa.
North America held the largest share of
the global intravenous immunoglobulin market in 2017 due to superior
health care infrastructure, strong regional economics, rise in
reimbursement initiatives, and easy access to advanced technology. The
region’s rapidly increasing geriatric population also drives the market.
The global population aged 60 and above stood at an estimated 962
million in the world in 2017, accounting for 13% of the total
population. This population is increasing at a rate of 3% per year.
Currently, Europe has the highest percentage of population aged 60 and
over (25%). Rapid aging will occur in other parts of the world as well
such as the U.S. and countries in Asia including China and India. Hence,
by 2050, all regions across the world, except Africa, will have nearly a
quarter or more of their populations aged 60 and above. The global
geriatric population is estimated at 1.4 billion in 2030 and 2.1 billion
in 2050, and could rise to 3.1 billion in 2100. Large number of
patients with chronic inflammatory demyelinating polyneuropathy (CIDP)
in North America also boosts demand for intravenous immunoglobulin
(IVIG). According to the Immune Deficiency Foundation (IDF), nearly 83
people per 100,000 in the U.S. suffer from primary immunodeficiency and
there are over 5 million undiagnosed cases in the country. The
intravenous immunoglobulin market in Europe is witnessing strong growth,
attributed to increase in inpatient population and rise in usage of
IVIG by end-users such as hospitals and clinics. Developing nations in
Asia Pacific such as China and India are poised to be the most promising
markets for IVIG in the near future. Key factors for the positive
outlook for the market in the region are large underserved patient
population, extensive development of health care infrastructure, and
rise in emphasis on research and development in the health care sector.
Hospitals was the largest end-user
segment of the global intravenous immunoglobulin market and is expected
to dominate the market during the forecast period. This is due to rise
in the number of patients opting for hospital treatment rather than
standalone clinics. The home care segment is likely to expand at a
steady CAGR of 8.9% from 2018 to 2026. This is attributed to various
benefits of home care. Patients getting IVIG infusions at home have
improved quality of life, as they get better control over day-to-day
activities. For instance, IVIG infusions at home care have reduced
scheduling clashes for patients.
Major companies operating in the global
intravenous immunoglobulin market include Shire plc, ADMA Biologics,
Inc., China Biologic Products, Inc., CSL Behring LLC, Grifols S.A.,
Kedrion S.p.A., LFB Biomedicaments S.A., Octapharma AG, and Sanquin
Plasma Products B.V.
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