Anticoagulants help control
the adhering of platelets and stop clotting proteins from binding
together. These are commonly used in the prevention and treatment of
venous thrombosis, pulmonary embolism, and other conditions of blood
clotting. Injectable anticoagulants are administered via different
routes of injectable drug delivery and are categorized into direct
thrombin inhibitors, factor Xa inhibitors, heparins,
low-molecular-weight heparin (LMWH) including dalteparin, enoxaparin,
and others. Heparin is an injectable anticoagulant widely used in
hospitals for rapid anticoagulation. LMWHs are highly acceptable and
preferred over heparins, as LMWHs can be self-administered when used in
home settings, while heparins are large sized molecules and bleeding is
associated with its use. Hence, these can only be injected at hospitals
through skilled professionals.
According to the World
Health Organization (WHO), prolonged traveling by passengers via
automobile, train, or airplane for more than four hours increases the
risk of developing venous thromboembolism. Coagulation disorders such as
venous thromboembolism (VTE), which includes both deep vein thrombosis
and pulmonary embolism, affect nearly 1 million people in the U.S. each
year. According to the Centers for Disease Control and Prevention,
500,000 to 900,000 people in the U.S. are affected by VTE each year. A
study published by Deutsches Arzteblatt International in 2013 revealed
that the annual incidence rate of diagnosed VTE in Germany stood at 150
to 200 cases per 100,000. The statistics above clearly indicate the
demand for safe, reliable, and affordable anticoagulants.
Rise in incidence of
coagulation and renal and heart diseases, commercialization of safe and
cost-effective biological origin anti-coagulants, enhanced quality
control measures, increase in geriatric population, and surge in
investment in research and development of biological origin drugs drive
the market. High cost of treatment is the only factor restraining the
market.
The global injectable
anticoagulants market can be segmented based on drug type, application,
and distribution channel. In terms of drug type, the market can be
categorized into low-molecular-weight heparin (LMWH) and direct thrombin
inhibitors (DTI). The low-molecular-weight heparin segment accounted
for the largest market share and is expected to witness rapid growth
during the forecast period. Based on application, the injectable
anticoagulants market can be classified into venous thromboembolism
(VTE), atrial fibrillation, acute coronary syndrome, and myocardial
infarction. In terms of distribution channel, the global market can be
divided into hospital pharmacies, retail pharmacies, and online
pharmacies. The hospital pharmacies segment accounted for the largest
market share and the trend is likely to continue during the forecast
period owing to rise in prevalence of deep vein thrombosis and increase
in hospital inpatients for different disease treatments. This, in turn,
is likely to drive the global injectable anticoagulants market during
the forecast period.
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Geographically, the global
injectable anticoagulants market can be segmented into five major
regions: North America, Middle East & Africa, Latin America, Asia
Pacific, and Europe. North America is the leading market for injectable
anticoagulants in terms of revenue, followed by Europe. The U.S. held
the largest share of the market in North America, followed by Canada.
The injectable anticoagulants market in Asia Pacific is likely to expand
at a high CAGR during the forecast period. This is attributed to
increase in patient population and rise in incidence of chronic
diseases, which has led to high demand for injectable anticoagulant
products.
Key players operating in the
global injectable anticoagulants market include Sanofi, Genentech
(Roche), Boehringer Ingelheim, Pfizer, The Medicines Company, B. Braun
Melsungen AG, Baxter, Aspen Otsuka, Fresenius SE & Co. KGaA, LEO
Pharma A/S, and Sagent Pharmaceuticals, Inc.
The report offers a
comprehensive evaluation of the market. It does so via in-depth
qualitative insights, historical data, and verifiable projections about
market size. The projections featured in the report have been derived
using proven research methodologies and assumptions. By doing so, the
research report serves as a repository of analysis and information for
every facet of the market, including but not limited to: Regional
markets, technology, types, and applications.
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