Fluorescent in situ hybridization (FISH)
is a molecular cytogenetic technique that uses fluorescent probes to
visualize and map an individual’s genetic materials. The technique uses
fluorescent microscope to identify fluorescent probes bound to the
chromosome. The FISH technique has wide applications in the diagnostics
industry such as identification of structural and numerical
abnormalities in chromosomes, characterization of marker chromosomes,
therapeutic drug monitoring, and rare and genetic disease
identification. The technique also has applications in clinical research
including gene mapping and characterization of somatic cell hybrids.
Three different types of FISH probes are available commercially, each
having different applications.
Report Overview @ https://www.transparencymarketresearch.com/fluorescent-in-situ-hybridization-probes-market.html
The global fluorescent in situ
hybridization probes market is projected to be driven by high prevalence
and rise in incidence rates of cancer and genetic disorders across the
globe. FISH probes are widely used for diagnosis, prediction of
outcomes, and clinical management of cancer and genetic disorders. Rise
in demand for targeted therapy in the treatment of most of the chronic
disorders in developed countries is likely to drive the global
Fluorescent In Situ Hybridization Probes market during the forecast
period. According to the World Health Organization, cancer is the second
leading cause of death across the world, accounting for 8.8 million
deaths in 2015. Moreover, an estimated 350 million people are living
with genetic and rare diseases across the globe. Favorable government
support to boost clinical R&D activities and increase in investment
by the private biopharmaceutical companies presents significant
opportunities in the Fluorescent In Situ Hybridization Probes market in
the near future. However, lack of skilled workforce in the emerging and
underdeveloped countries and high cost of FISH technology restrain the
global fluorescent in situ hybridization probes market.
The global fluorescent in situ
hybridization probes market can be segmented based on probe type,
application, end-user, and region. In terms of probe type, the global
Fluorescent In Situ Hybridization Probes market can be classified into
locus specific probes, alphoid or centromeric repeat probes, and whole
chromosome probes. Locus specific probes are genomic clones that bind to
particular region on chromosome. These probes are commonly used to
identify and determine desired gene location, its amplification, gene
loss, gene split, and gene translocation. Alphoid probes are generated
by hybridizing the specific chromosomal structure having repetitive
sequences on chromosome. These probes are used to determine whether an
individual has desired number of chromosomes. Whole chromosome probe is a
collection of smaller probes which binds to different sequences. These
probes are widely used to examine chromosomal abnormalities. In terms of
application, the global Fluorescent In Situ Hybridization Probes market
can be bifurcated into oncology research and genetic diseases. The
oncology research segment is projected to account for significant
Fluorescent In Situ Hybridization Probes market share by 2026. In terms
of end-user, the fluorescent in situ hybridization probes market can be
divided into hospitals & diagnostic laboratories, clinical research
organizations, biotechnology companies, and academic & research
institutes.
Geographically, the global fluorescent in
situ hybridization probes market can be segmented into North America,
Europe, Asia Pacific, Latin America, and Middle East & Africa. North
America is projected to account for the largest share of the global
Fluorescent In Situ Hybridization Probes market owing to high prevalence
of cancer especially breast cancer, well-established R&D
infrastructure, high clinical R&D budgets, and presence of large
number clinical research organization. Europe is anticipated to account
for the second largest market share by 2026. The fluorescent in situ
hybridization probes market in Europe is expected to grow at a rapid
pace during the forecast period. The Fluorescent In Situ Hybridization
Probes market is Asia Pacific is likely to expand at a moderate CAGR
during the forecast period owing to large population with cancer and
genetic disorders, increase in investments in the biotechnology industry
in the emerging countries such as India and China, and rise in clinical
R&D activities in the region.
Key players operating in the global
fluorescent in situ hybridization probes market include
Creative-Biolabs, Abnova Corporation, Thermo Fisher Scientific Inc.,
Agilent Technologies, Genemed Biotechnologies, Inc., F. Hoffman-La Roche
AG, Biosearch Technologies, Inc., Mirus Bio LLC, Horizon Diagnostics,
and Oxford Gene Technology.
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