Wednesday, July 31, 2019

Antiplatelet Drugs Market Growth Focusing on Trends & Innovations during the Period until 2026

Global Antiplatelet Drugs Market: Overview

Globally, the number of people suffering from ischemic strokes has increased, especially in developed countries. People suffering from myocardial infarction and stent thrombosis have also gone up. The use of antiplatelet drugs helps in reducing the ability of platelets to stick together and obstructs blood clots formation that leads to these diseases. Thus, its demand has grown significantly in the past few years.

Advancement in pharmaceuticals, proliferation of anticoagulant/antithrombotic drugs, and rising thrombolytic events are the key drivers for the antiplatelet drugs market. Antiplatelet drugs help in effective arterial circulation and are widely used in the primary and secondary prevention of cardiovascular or thrombotic cerebrovascular disorders.


The global antiplatelet drugs market could be classified on the basis of disease type, drug class, and distribution channel. Based on distribution channel, the market is segmented into online pharmacies, retail pharmacies, and hospital pharmacies. Based on drug class, the market is segmented into platelet aggregation inhibitors, glycoprotein platelet inhibitors, and protease-activated receptor-1 antagonists.
The report provides a detailed description of the global antiplatelet drugs market. It provides information focusing on the drivers, restraints, trends, and opportunities affecting the growth of the market. Furthermore, regional analysis with key segment analysis derived through facts and figures is also presented in the report.


Global Antiplatelet Drugs Market: Trends and Opportunities

According to the data provided by the American Heart Association, there are about 800,000 individuals suffer from stroke every year in the U.S. among these three out of four-experience stroke the very first time. Of these, 87% are ischemic strokes. Moreover, based on the data provided by the Centers for Disease Control and Prevention, 735,000 people have a heart attack in Latin America and North America. Of these 525,000 people experience heart attack the very first time. Thus, the growing trend of these diseases has led to the growth of the antiplatelet drugs market.

Global Antiplatelet Drugs Market: Geographic Analysis

Regions taken into consideration while analyzing the growth of the antiplatelet drugs market are Europe, Asia Pacific, North America, Latin America, and the Middle East and Africa. Among these regions, in 2016, North America held the larger share in the market. A large number of patients suffering from myocardial infarction led to the dominance of this region. In the same year, Europe held the second position in the market due to the rise in research and development on antiplatelet drugs. On the other hand, Asia Pacific market is expected to grow at a significate rate owing to rising government initiatives to reduce the number of deaths caused by stent thrombosis, ischemic stroke, and myocardial infarction.


Global Antiplatelet Drugs Market: Competitive Landscape


The competitive landscape given in the report on the global antiplatelet drugs market provides detail description about the prominent players operating in the market. Leading players in the market are implementing advanced business development strategies to get a strong hold in the global market. Sanofi, Otsuka Pharmaceutical Company, Ltd., Bristol-Myers Squibb Company, Daiichi Sankyo, Inc., AstraZeneca, and Boehringer Ingelheim GmbH are some of the prominent players operating in the market.

Bronchial Thermoplasty Market Industry Analysis, Size, Growth, Trends and Demand 2026

Bronchial thermoplasty is an evolutionary therapy for treating asthma, a leading chronic disease across the globe. Asthma is one of the most common chronic diseases among children which worsens with age. It is a complex inflammatory disease caused by genetic mutation or other environmental factors. In asthma, the airway muscles become hypersensitive to various allergens, triggering inflammation of the muscular wall of airway tract, and consequently narrowing the airway passage. The inflammation eventually leads to thickening of smooth muscle of airway tract, which results in restricted air flow affecting the breathing process. Treatment of asthma involves administration of various drugs such as albuterol, steroids and beta agonists through inhalers and nebulizers. However, bronchial thermoplasty is recommended in severe cases, where asthma control with these medications is less effective.


According to World Health Organization (WHO) report published in 2017, 235 million people across the world were affected with asthma in 2015 and it accounted for 383,000 deaths globally. Incidence rate of asthma is rising among children due to increase in susceptibility to various airborne allergens and other associated risk factors. According to the United States Environmental Protection Agency (EPA), prevalence of asthma among children was 8.4% in the U.S. in 2015. According to the Centers for Disease Control and Prevention, during 2006 to 2010among the total asthma patients in the U.S., uncontrolled asthma was evident in 38% children and 50% adults. Rise in number of asthma cases drives demand for more effective treatments. This has induced the industry to develop new therapeutic devices such as bronchial thermoplasty. However, bronchial thermoplasty is an expensive procedure and requires skilled operator and well developed infrastructure. Moreover, restricted patient selection criteria for bronchial thermoplasty restrains its adoption among physicians.


Bronchial thermoplasty is a minimally invasive procedure, which involves provision of radiofrequency energy to bronchial wall through a catheter. A bronchoscope is inserted through the nasal cavity through which a thermoplasty catheter is advanced to the therapy sight. The catheter comprises four electrodes in the shape of a basket and temperature sensors. Bronchial thermoplasty is performed in three settings separated by three weeks’ time. In each setting, different parts of the bronchi are targeted for therapy, such as left lower lobe and right lower lobe are treated in first and second sittings, while upper lobes are treated in the third sitting. The electrodes provide temperature of about 65ยบ C for 10 seconds to 15 seconds, which reduces the chances of adverse effects. The procedure lasts for 30 minutes to 45 minutes. Bronchial thermoplasty is claimed to improve the quality of life of asthma patients and also reduces the recurrence of asthma attacks in long term studies. However, bronchial thermoplasty is recommended as an adjuvant therapy with asthma medications.


In terms of region, the global bronchial thermoplasty market can be segmented into North America, Europe, Asia Pacific, and Rest of the World. Bronchial thermoplasty is a considerably new therapy procedure. North America is projected to account for leading share of the global market during the forecast period, due to high adoption of technically advanced treatment devices and techniques. Despite being a new method, large number of public and private health care payers are considering reimbursements for these procedures on a case-to-case basis. This augments the bronchial thermoplasty market in North America. Europe is anticipated to account for a significant share of the global market during the forecast period. Well-established health care infrastructure and trend of medical tourism in countries in Central and Eastern Europe are the key factors driving the market in Europe. Increase in expenditure to develop health care infrastructure and rise in private health care expenditure in emerging markets such as China and India are anticipated to boost the market in Asia Pacific.


Presently, Boston Scientific Corporation is the only manufacturer and supplier of bronchial thermoplasty device brand named Alair. In October 2010, the company completed the acquisition of privately owned Asthmatx, Inc., the developer of Alair. This system received the U.S. FDA approval in April 2010 and CE Mark in 2011. In October 2013, the Chinese FDA approved the Alair system for treating patients with persistent asthma.

Chronic Lymphocytic Leukemia Market Overview by Increasing Demand and Sales 2018 - 2026

Chronic lymphocytic leukemia is a common type of leukemia found in adults. In this type of cancer, lymphocytes, i.e., white blood cells develop in the bone marrow and travel through the blood. The lymphocytic leukemia cells are majorly found in the lymph nodes and other tissues. There are two types of chronic lymphocytic leukemia, one of which grows slowly, while the other type is fatal. Generally, chronic lymphocytic leukemia do not cause any symptom for a long time. Symptoms generally observed are swollen lymph nodes, fatigue, and easy bruising. Usually, the preferred treatment for chronic lymphocytic leukemia is chemotherapy. Stem-cell transplant is used in rare cases. According to an article published by Apollo Hospitals, an estimated one million cases of chronic lymphocytic leukemia are diagnosed in India every year. Cancer statistics states that, in England, 1 in every 155 men and 1 in every 260 women are affected with chronic lymphocytic leukemia in their lifetime.


Increasing incidence of cancer across the globe, innovative drug therapy, fast regulatory approval process, and aggressive pipeline for chronic lymphocytic leukemia treatment drugs are the factors driving the growth of the global chronic lymphocytic leukemia market. However, lack of awareness regarding symptoms at an early stage, low accessibility of treatment options in under-developed countries, increasing use of generic products across countries hampering the demand for branded drugs, and adverse events occurring during the treatment, such as side effects of chemotherapy, are restraining the growth of the global market.

The global chronic lymphocytic leukemia market can be segmented according to type of cancer, type of therapy, route of administration, end-user, and geography. In terms of type of cancer, the market can be classified into B-cell chronic lymphocytic leukemia, T-cell chronic lymphocytic leukemia, and natural chronic lymphocytic leukemia. On the basis of type of therapy, the market can be divided into targeted therapy or chemotherapy. In terms of route of administration, the market can be segmented into intravenous, subcutaneous, intrathecal route, intramuscular, and oral. According to end-user, the global chronic lymphocytic leukemia market can be classified into hospitals, ambulatory surgical centers, cancer institutes, and research & academic institutes.


In terms of region, the global chronic lymphocytic leukemia market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America dominates the global market, followed by Europe. According to the World Health Organization, cancer is the leading cause of death across countries. According to the National Cancer Institute, it is estimated that in 2018, in the U.S., about 1,735,350 new cases of cancer will be diagnosed and an approximate number of 609,640 number of patients will die due to cancer. Asia Pacific holds significant potential for growth for the market. Investment in the field of research and development for new drugs and in pharmaceutical and biotechnology companies in India, China, and Japan are the key factors driving the growth of the market in Asia Pacific. Rise in disposable income in the countries of Latin America, such as, Mexico and Brazil, is expected to boost the growth of the chronic lymphocytic leukemia market in the region. Developing health care infrastructure in the Middle East countries is projected to accelerate the growth of the chronic lymphocytic leukemia market in the region. Furthermore, increasing government investment in health care and growing presence of key players in Africa are anticipated to boost the market in Middle East & Africa.



Prominent players of the global chronic lymphocytic leukemia market are AbbVie, Inc., Arno Therapeutics, Genzyme Corporation, Gilead Sciences, Johnson &Johnson, Novartis AG, Ono pharmaceuticals Co. Ltd., F. Hoffmann-La Roche Ltd., Teva Pharmaceutical Industries Ltd., TG Therapeutics, Xeme Biopharma Ziopharma Oncology, Inc., among others.

Self-monitoring Blood Glucose (SMBG) Market Competitive Analysis 2018 - 2026

Global Self-monitoring Blood Glucose (SMBG) Market: Overview 

Glucose monitoring is a necessary step towards managing diabetes. Diabetes is a kind of clinical condition where the blood glucose level increases due to the pancreas inability in producing insulin. Self-monitoring blood glucose helps diabetic patients in deciding the dosage of insulin, food intake, and type of physical exercise needed for a day. SMBG or self-monitoring blood glucose is a modern procedure of diabetes management where the blood glucose meters are used for checking glucose levels. Such procedure provides a precise measure of capillary glucose concentrations. Apart from blood glucose meters, self-monitoring blood glucose technology also uses lancets, and test strips for controlling glycaemia.


The global self-monitoring blood glucose (SMBG) market is mainly segmented on the basis of product type, distribution channel, and geography. Under product type, glucose meters, lancets, and test strips are the prominent segments comprising the market. Whereas, with respect to distribution channel, key segments present in the global self-monitoring blood glucose (SMBG) market are online retailers, hospital pharmacies, retail pharmacies, and mail order pharmacies. Geographically, the key regions comprising the market are Latin America, the Middle East and Africa, Asia Pacific, North America, and Europe.

Global Self-monitoring Blood Glucose (SMBG) Market: Key Trends 

Growing incidences of diabetes among aging population globally, rising demand for controlling glycemic, and increasing need for preventing hypoglycemia are factors driving the demand in the global self-monitoring blood glucose (SMBG) market. Self-monitoring blood glucose procedure helps in improving hypoglycemia recognition and enables patients in authorizing harmful effects of pharmaceutical intervention. Rising demand for continuously checking blood sugar, and increasing need for tracking blood glucose level in order to stay healthy and fit are also boosting the global self-monitoring blood glucose (SMBG) market.


Furthermore, growing government and non-government  initiatives in controlling diabetes, rising awareness about the surge in diabetic epidemic, and increasing demand for preventive measures against glycaemia are also fueling the demand in the global self-monitoring blood glucose (SMBG) market. Apart from this, rapid incorporation of technology into SMBG products such as glucometer helps in monitoring blood glucose level effortlessly. Such factors is anticipated to propel the global self-monitoring blood glucose (SMBG) market.

Global Self-monitoring Blood Glucose (SMBG) Market: Regional Outlook 

With respect to geography, North America is leading the global self-monitoring blood glucose (SMBG) market as the region has seen rapid establishment of healthcare industry. Growing governments funding for developing new and innovative products for treating diabetes are also responsible for fueling the self-monitoring blood glucose (SMBG) market in the region. However, rising number of people suffering from diabetes in Asia Pacific makes this region exhibit a substantially fast growth. 


Global Self-monitoring Blood Glucose (SMBG) Market: Competitive Landscape 


Key players operating in the global self-monitoring blood glucose (SMBG) market include Abbott Laboratories, LifeScan, Ascensia Diabetes Care Holdings AG, B. Barun Melsungen AG, Johnson & Johnson, and Hoffmann-La Roche Ltd. Each of these companies has been broadly described in the report in terms of prime strategies, revenue gained in recent times, and growth projected to attain in forthcoming years, in terms of market shares.

Proteomics Market : Competitive Strategies And Forecasts to 2026

Proteomics can be defined as the study of proteomes. Proteomes are a set of proteins which are produced in a system, organism, or any biological context. Proteomes vary from cell to cell and changes over a period of time. Proteomics is used in various applications, such as, to investigate protein expression, in transcriptional and post transcriptional studies, metabolic pathways, to study protein interaction in diseases viz. cancer, to study localization of sub cellular proteins, etc. Proteomics can be studied using various technologies, such as, mass spectrometry, gel-based techniques, and others.


The global proteomics market is expected to grow at a significant CAGR during the forecast period. Increasing research & development activities in the healthcare industries, rising demand for personalized medicines, and increasing activities of drug discovery are some of the important factors expected to contribute to the growth of the global proteomics market during the forecast period. Rise in use of proteomics to study cancer genes and protein interaction in cancer genes is projected to drive the growth of the global proteomics market due to high prevalence of cancer across the world. Factors such as application of proteomics in the diagnosis of infectious diseases, technological advancement, increase in health care expenditure, rise in awareness, etc. are the other factors likely to boost the growth of the global proteomics market during the forecast period. However, inadequate funding and lack of awareness regarding the application of proteomics in developing countries are anticipated to restrain the growth of global proteomics market during the forecast period.


The global proteomics market can be segmented on the basis of product, services, application, and region. Based on product, the global proteomics market can be divided into instrumentation and reagents. The instrumentation segment can be further classified into spectrometry, chromatography, X-ray, immunoassay, electrophoresis, and others. In terms of services, the global market can be segmented into analytical laboratory services, sequencing, protein identification, bioinformatics, and others. The anatomical laboratory services segment is expected to hold a significant share of the market during the forecast period due to effectiveness of services provided by anatomical laboratories in diagnosis and drug discovery. On the basis of application, the global proteomics market can be categorized into clinical diagnosis, drug discovery, and others. The clinical diagnosis segment is expected to hold a significant share of the market during the forecast period due to rise in prevalence of cancer, increase in incidence of infectious diseases, etc. across the globe.

The global proteomics market is expected to grow at significant rate in all geographical regions. Based on region, the global market can be segmented into North America, Europe, Asia Pacific, Middle East & Africa, and Latin America. North America is expected to dominate the global proteomics market throughout the forecast period. Factors influencing the growth of market in North America include rise in funding from government, increase in research activities, high awareness regarding applications of proteomics, improved health care infrastructure, high health care expenditure, and rise in prevalence of cancer in the region. Europe is projected to be the second leading market for proteomics during the forecast period due to increase in cancer research activities, high funding from the government, and presence of key market players in the region. Driver The proteomics market in Asia Pacific is estimated to expand at a significantly high CAGR during the forecast period. Growth drivers of the proteomics market in the region include high prevalence of cancer, rising health care expenditure, presence of a large number of drug manufactures in countries such as India and Japan leading to increase in drug discovery, and high prevalence of infectious diseases in the region.



In order to maintain a significant position in the global proteomics market, key players are adopting strategies, such as, mergers & acquisitions, geographical expansion, research & development, etc. Leading players operating in the global proteomics market include GE Healthcare, Bio-Rad Laboratories, Inc., Danaher Corporation, and PerkinElmer, Inc.

Anticoccidial Drugs Market Segmentation Detailed Study with Forecast to 2026

Coccidiosis is a widespread disease caused by a single cell parasite that can be seen only with the help of a microscope. Every livestock species as well as wild animals can be infected by coccidiosis, which is particularly prevalent when animals or birds are grouped together in significant numbers. The disease results in lower egg production in chickens and is responsible for mortality in the flock. Commonly, three to four species of coccidian are responsible for the outbreak of the disease. The severity of the disease depends on the number of oocyte ingested and on the species of coccidia. Anticoccidial drugs are those entities that combat the progression of coccidiosis in animals or birds. Anticoccidials are administered in the feed to prevent disease and minimize the economic loss often associated with sub-acute infections. Prophylactic use of anticoccidial drugs is preferred many a times as most of the damage occurs before clinical signs become apparent.


The anticoccidial drugs market can be segmented based on action, drug entity, and region. In terms of action, the anticoccidial drugs market can be classified into coccidiostatic and coccidiocidal. Based on drug entity, the anticoccidial drugs market can be categorized into ionophores and synthetic anticoccidials. The ionophores segment can be further divided into monovalent, monovalent glycoside, and divalent. Ionophores are the fermentation products of fungi species. They are extensively used as anticoccidial agents. Salinomycin, lasalocid, and monensin are the most commonly used ionophores. In terms of geography, the anticoccidial drugs market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa.
North America accounts for a significant anticoccidial drugs market share in terms of revenue, due to a well-established infrastructure in immunological research, highly organized farming, increased demand for animal protein, high pet ownership, greater emphasis on prevention and wellness by veterinarians, and rise in spending on medicine. According to the USDA Economic Research Service, poultry is the fastest growing meat product in the organic products anticoccidial drugs market in the U.S.. The size of the poultry segment is around US$ 56 Mn. The segment expanded at an annual growth of 33% through 2008 (USDA, 2008). The high consumption of meat is expected to propel the anticoccidial drugs market in North America. Europe is a prominent region of the anticoccidial drugs market, owing to a highly developed health care industry, high government funding for the development of veterinary medicines, increased awareness among people, and high consumption of meat. The Biotechnology and Biological Sciences Research Council (BBSRC) donated GBP 5.7 Mn for the development of poultry vaccines to the London School of Hygiene and Tropical Medicine in December 2015.


The anticoccidial drugs market in Asia Pacific is expanding at a robust pace due to high rate of development in veterinary medicines and increase in government initiatives. Nowadays, major pharmaceutical companies are outsourcing their drug development services to various countries such as China, Singapore, Malaysia, and India, which is eventually propelling the growth of the anticoccidial drugs market in this region. The global anticoccidial drugs market is witnessing considerable growth owing to a rise in disposable income of people in emerging countries. Disposable income is increasing in emerging countries such as India and China, which results in a change in lifestyle and high demand for animal protein foods such as meat, milk, etc.. Increase in disposable income is likely to boost demand for veterinary pharmacies. Middle East and Latin America are expected to be the prospective regions of the anticoccidial drugs market in the near future due to rapidly developing pharmaceutical and biotechnology industries.


Some of the major players operating in the anticoccidial drugs market are Bayer Animal Heath, Boehringer Ingelheim, Ceva Santรฉ Animale, Elanco, Novartis Animal Health, Merck Animal Health, Merial, Virbac S.A., and Zoetis.


The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

Anticaries Treatments Market Size, Status and Forecast to 2026

Dental caries occur when the acid from plaque erodes the tooth enamel and forms cavities. Caries is a common dental disease, prevalent in both developed and developing countries, affecting every stratum and age group of the society. The FISABIO Foundation discovered a new bacterial species named Streptococcus dentisani, which acts as a shield against caries-causing bacteria, producing a substance that inhibits them and prevents caries. Streptococcus dentisani bacteria is used as a preventive probiotic product to improve oral health in the food and cosmetic industries (mouthwash, toothpaste). Probiotic solutions are expected to be a groundbreaking approach toward anticaries treatment as these solutions have the potential to improve health and reduce health care expenditure. Anticaries treatment is considered an attractive concept for next-generation anticavity therapy, as it has the potential to prevent tooth replacement or other dental surgical replacements required due to cavity formation. The use and availability of different types of anticaries treatments have evolved over the past century; however, further research is ongoing in order to develop its more clinical applications and reduce the adverse effects associated with the use of anticaries treatments.


A major factor driving the anticaries treatments market is the high incidence of dental problems globally. Rise in incidence of periodontics among young adults and increase in demand for stem cell anticaries treatment techniques, especially among the geriatric population, are the other factors anticipated to drive the anticaries treatments market during the forecast period. Favorable price of anticaries products and emergence of new technologies using an anticaries product as a functional food, mouthwash, toothpaste, chewing gum, etc. are expected to propel the global anticaries treatments market. According to the World Health Organization, complete loss of teeth affects approximately 30% of the geriatric population in the age group of 65-74 years. However, prevalence rates of anticaries are increasing in low and middle income countries. Factors, such as, preference for endodontic treatment over anticaries treatment in major dental surgeries and local inflammatory activity which results in chronic complications and dental replacements are projected to restrain the growth of the anticaries treatments market during the forecast period.


The global anticaries treatments market can be segmented on the basis of product type, end-user, and region. In terms of product type, the anticaries treatments market can be categorized into topical solution, gel-based, foam-based, toothpaste, and others. The gel-based segment accounted for a prominent share of the global anticaries treatments market in 2017, due to increasing prevalence of dental surgery and rising demand for cosmetic surgery, especially in the emerging economies, such as, China, Brazil, and India. In terms of end-user, the anticaries treatments market can be divided into cosmetic industry, home care, dental clinics, and others.

In terms of region, the global anticaries treatments market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America is projected to dominate the global anticaries treatments market during the forecast period due to increasing dental services and stem cell research in the region. According to the Dental Health Services, in 2015, total expenditure on dental services in Canada amounted to US$ 13.6 Bn. Expenditure of the private sector was estimated at US$ 12.7 Bn, while that of the public sector at US$ 846 Mn. In April 2017, Unilever launched an in-clinic remineralisation regime to regenerate professionally advanced enamel serum. The Unilever brand claimed 82% of the enamel mineral regenerated after 3 days. Furthermore, increasing prevalence of dental cavities and periodontics, especially in the developing countries, such as, China and India has boosted the demand for dental surgery. According to the World Health Organization, nearly 60% to 90% of school children and nearly 100% of adults have dental cavities. The incidence of dental surgery, general prosthetic fixation, periodontal inflammation, and other dental diseases is increasing in Asia Pacific. This, in turn, is anticipated to fuel the demand for cost-effective aesthetic and dental surgeries. These factors are projected to drive the anticaries treatments market in Asia Pacific between 2018 and 2026.



Key players operating in the global anticaries treatments market include Unilever, Ocata Therapeutics, ICPA Health, GlaxoSmithKline plc, and Church & Dwight, Inc.

Tetanus Human Monoclonal Antibodies Market : Competitive Strategies, Regional Analysis Forecast 2026

Antibodies derived through cell division from a single parent cell are termed as monoclonal antibodies. Monoclonal antibodies bind to the same epitope, which means that they have monovalent affinity. A bacterium called Clostridium tetani causes an infectious disease by producing a neurotoxin called the tetanus toxin. These toxins can also be responsible for a neuroparalytic syndrome called botulism. Tetanus monoclonal antibodies specifically bind to the tetanus toxin and neutralize the toxin. These antibodies are developed mostly on hybrid cell lines. These antibodies can be used for passive immunization, as the current immunoglobulin for the disease is derived from horses. It can also be used in research studies.


The global tetanus human monoclonal antibodies market is estimated to expand at a steady pace during the forecast period. According to the WHO, approximately 49,000 newborn babies died of the infection by neonatal tetanus in 2013 worldwide. Thus, high prevalence and incidence of tetanus is one of the most important factors expected to drive the tetanus human monoclonal antibodies market during the forecast period. Furthermore, advantages offered by monoclonal bodies in passive immunization such as more rapid action than vaccines, quicker development, and easier prediction of safety compared to vaccines are some of the factors likely to drive the global market from 2018 to 2026. Furthermore, rise in awareness about children’s health, increase in health care expenditure, development of health care infrastructure, and surge in research activities are driving the the global tetanus human monoclonal antibodies market. Some of the factors restraining the market are high research and development costs, short duration of protection, and lack of awareness among people in developing countries.


The global tetanus human monoclonal antibodies market can be segmented based on product, application, and region. Based on product, the market can be divided into light-chain antibodies, heavy-chain antibodies, mouse antibodies, goat antibodies, and others. Based on application, the global tetanus human monoclonal antibodies market can be classified into passive immunization and research activities. The research activities segment is expected to hold a significant share of the market during the forecast period, due to extensive research activities related to development of monoclonal antibodies for immunization.

Geographically, the global tetanus human monoclonal antibodies market has been divided into North America, Latin America, Europe, Asia Pacific, and Middle East & Africa. North America is anticipated to dominate the global market during the forecast period. Surge in investments from government and public sectors increasing number of programs to eradicate tetanus from the region, rise in awareness, extensive research on Clostridium sp., and high health care expenditure are a few factors propelling the market in North America. The market in Asia Pacific is anticipated to register a rapid growth rate during the forecast period. Asia Pacific is a highly lucrative market for tetanus human monoclonal antibodies, due to high prevalence of tetanus, government immunization programs, increasing investments in R&D activities, entry of new manufacturers in India and China, and surging medical tourism in the region. Furthermore, rising awareness about newer research techniques, improvement in genetic engineering, and exposure of children to soil are some of the factors anticipated to drive the market in the region during the forecast period.



Some of the prominent players operating in the global tetanus human monoclonal antibodies market are Antagen Pharmaceuticals, Inc., Thermo Fisher Scientific Inc., and BioScience.

Wearable Cardioverter Defibrillators Market : Insights and Emerging Trends by 2026

A wearable cardioverter defibrillator is a lightweight, easy to wear device worn by patients who are at a high risk of a sudden cardiac arrest (SCA). A wearable cardioverter defibrillator is an external device that mainly consist of two components, garment and monitor. The garment is worn under the clothing as a vest to continuously to monitor the heart and on detection of an arrhythmia, it releases a shock to restore heart’s normal rhythm. The monitor is worn around the shoulder using a shoulder strap or around the waist. It records the intensity of the arrhythmia. This whole process happens within a minute, as SCAs are unpredictable and need to be treated via a shock treatment to save victim’s life. A wearable cardioverter defibrillator is an alternative treatment method used to prevent SCAs in non-pacemaker-dependent patients who are awaiting an implant of a cardioverter defibrillator.

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According to the World Health Organization (WHO), cardiovascular diseases are a leading cause of mortality globally. These diseases account for 31% of total global mortality. According to the Sudden Cardiac Arrest Association, in the U.S., more than 325,000 people succumb to SCA each year and among those the survival rate is only 10%. According to the European Resuscitation Council, SCAs cause approximately 20% of all deaths in Europe. As per statistical projection of the United Nations (UN), the global number of people over the age of 60 years is projected to increase from 901 million in 2015 to 1.4 billion by 2030.

Cardiac arrest is a public health issue, which has a severe impact on the wellbeing of human health. Prevalence of sudden cardiac arrest is directly proportional to the increasing population, worldwide. Rapid growth in the global geriatric population and rise in the number of sudden cardiac arrest cases are driving the wearable cardioverter defibrillators market. Increasing per capita income of people, rising awareness about cardiac diseases and cardiac arrests are fuelling the wearable cardioverter defibrillators market in developing countries. Technological advancements in wearable cardioverter defibrillator devices, such as reduction in the noise of electrodes, improvements in signal detection, weight and size reduction of the device to make it more comfortable for the patient, is another key factor boosting the wearable cardioverter defibrillators market. However, less awareness about the wearable cardioverter defibrillator device in developing countries and device lacking potential to detect atrial arrhythmia signals are key restrains of the market.

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The global wearable cardioverter defibrillators market can be segmented based on application, end-user, and region. In terms of application, the market can be segregated into congenital heart diseases, inherited arrhythmias, and peripartum cardiomyopathy. Based on end-user, the wearable cardioverter defibrillators market can be divided into clinics, hospitals, and home care settings, and others.

In terms of region, the global wearable cardioverter defibrillators market can be categorized into North America, Europe, Latin America, Asia Pacific, and Middle East & Africa. North America accounts for a dominant share in the global wearable cardioverter defibrillators market owing to the increase in awareness among the people regarding sudden cardiac arrests and wearable cardioverter defibrillator devices. Europe constitutes a large share of the market due to technological advancements and rise in the number of cardiac arrest and SCA incidences in the region. The market in Asia Pacific is expanding at a rapid pace owing to the increase in government support, rise in health care expenditure, and surge in per capita income. Increasing demand for wearable cardioverter defibrillator devices in Asia Pacific due to Rise in awareness about these devices, government support, rise in per capita income are some of the factors likely to fuels the market in the region.

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Prominent players in the global wearable cardioverter defibrillators market include Medtronic, Cardiac Science, LivaNova, Boston Scientific Corporation, St. Jude Medical LLC, Koninklijke Philips N.V., Nihon Kohden Corporation, Defibtech LLC, and Physio-Control Inc.

Nonsurgical Aesthetic Procedures Market Boosting the Healthcare Industry Worldwide

Nonsurgical aesthetic procedures are either minimally-invasive or non-invasive procedures. Nonsurgical aesthetic procedures are not permanent and need to be repeated over a period of time to maintain the results or effects. Nonsurgical aesthetic procedure does not involve any incision on the skin for treatment. It is generally preferred by people who are of forty years of age or above. Nonsurgical aesthetic procedures involve the use of botulinum toxin, hyaluronic acid, medical devices, and lasers for treatments, such as, skin tightening, dermal fillers, skin resurfacing, and hair removal. These procedures offer several benefits, such as, zero downtime and zero incision and scar, reduced risk of complication, no hospitalization, and reduced cost of treatment over surgical procedures.

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Increasing popularity and awareness of nonsurgical aesthetic procedures and low cost of these procedures, as compared to surgical ones, are the factors driving the global nonsurgical aesthetic procedures market. Other factors fuelling the market growth are, continuously rising number of surgeons performing minimally invasive nonsurgical aesthetic procedures and reduced risk of complications. Factors such as upsurge in the rate of medical tourism and less recovery time after the procedure have boosted the nonsurgical aesthetic procedures market across the globe. However, lack of awareness and stringent government regulations regarding minimally invasive procedures are expected to hinder the market growth in the near future. Furthermore, low per capita income of people in underdeveloped regions and low health care expenditure by governments are anticipated to impact the growth of the nonsurgical aesthetic procedures market negatively during the forecast period.

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As per data published by The American Society for Aesthetic Plastic Surgery, in 2017, the injectable segment of the nonsurgical aesthetic procedures market accounted for the leading market share in North America, with around 2.34 million surgeries and 5.1% increase in the number of surgery as compared to that of the previous year. Chemical peel surgeries increased by 15.9% and nonsurgical skin tightening treatments increased by 15.1% in the U.S. According to The International Society of Aesthetic Plastic Surgery, in 2016, botulinum toxin surgeries showed an increase of around 7% all over the globe in terms of number of surgeries performed. As estimated by The American Society for Aesthetic Plastic Surgery, nonsurgical aesthetic procedures are highly popular in the age group of 35-50 years.

The global nonsurgical aesthetic procedures market can be segmented based on type, end-user, and region. In terms of type, the market can be classified into injectable, facial rejuvenation, and others. The injectable segment can be further classified into botulinum toxin, hyaluronic acid, and others. The facial rejuvenation segment can be categorized into chemical peel, nonsurgical skin tightening, microdermabrasion, laser skin resurfacing, and others. Based on end user, the nonsurgical aesthetic procedures market can be segmented into hospitals, aesthetic surgery centers, and others.

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In terms of region, the global nonsurgical aesthetic procedures market can be segmented into North America, Europe, Latin America, Asia Pacific, and Middle East & Africa. North America leads the global nonsurgical aesthetic procedures market owing to rise in awareness regarding these procedures and their growing popularity due to the benefits offered by these procedures. According to The International Society of Aesthetic Plastic Surgery, in 2016, around 1.11 million botulinum toxin and 650,232 hyaluronic acid procedures were performed in the U.S. Furthermore, around 105,138 chemical peel procedures and 75,834 nonsurgical skin tightening procedures were executed in the country. Europe accounts for a prominent share of the global nonsurgical aesthetic procedures market due to low cost of these procedures and reduced risk of complications associated with them. The nonsurgical aesthetic procedures market in Europe region is expected to grow at a significant rate during the forecast period. Asia Pacific is a rapidly growing market for nonsurgical aesthetic procedures owing to continuous rise in the number of surgeons performing these procedures. The nonsurgical aesthetic procedures market in Asia Pacific is expected to experience a swift growth in the near future owing to growth of medical tourism in the region.


Key players operating in the global nonsurgical aesthetic procedures market are Allergan plc, Cynosure, A Hologic Company., Merz Pharma GmbH & Co. KGaA, Galderma (Nestle Skin Health), Alma Lasers, AQTIS Medical BV, BTL Group of Companies, Cutera, Genesis Biosystems, Inc., Hangzhou Techderm Biological Products Co., Ltd., and Lumenis, Medytox Inc.

Tuesday, July 30, 2019

Combination Vaccines Market Highly Favorable to the Growth Rate by 2017 - 2025

A combination vaccine is a mixture of two or more than two vaccines that could be administered separately, which is put into a single shot. The combination vaccine offers the same protection to children as the two vaccines administered separately, but with a few number of shots. Disease prevention and eradication of preventable diseases are eventual and instant goals of immunization and the method to achieve these goals is maintaining vaccine coverage. Vaccine coverage can be maintained by using combination vaccines, as they simplify the schedule of vaccination and reduce the number of injections required.


The development of combination vaccines for protection against multiple diseases was initiated by combining separate vaccines against tetanus, diphtheria, and pertussis into a single product. This combination of diphtheria, pertussis, and tetanus vaccines into a single product has been crucial for protection of children. Similarly, the combination of inactivated polio, hepatitis B, and Haemophilus influenzae vaccines has enabled the inclusion of these vaccines into recommended immunization schedules, by reducing the number of injections required. This has also increased the immunization compliance. However, numerous challenges are faced while developing these combinations including the abridged response to the Haemophilus influenzae vaccine when administered in combination. There is immediate need to expand the safety profile of the tetanus, diphtheria, and pertussis combination vaccine.

An important development in the field of combination vaccines was replacement of whole-cell pertussis antigens with less reactogenic acellular antigens. This paved the way for combining of tetanus, diphtheria, and acellular pertussis antigens with other routinely used vaccines such as inactivated Haemophilus influenzae vaccine, polio vaccine, and hepatitis B vaccine. Another significant combination vaccine that gives protection against more than one disease is the mumps, measles, and rubella (MMR) vaccine. A few examples of commonly used combination vaccines in children are: ProQuad, which combines MMR and varicella; Pediarix, which combines Hep B, DTaP, and IPV; Pentacel, which combines DTaP, IPV, and Hib; and Kinrix, which combines IPV and DTaP.


The global combination vaccines market is driven by increase in the prevalence of infectious diseases. Infectious diseases is one of the most leading causes of illnesses and deaths worldwide. In developing countries with weak health care infrastructure, influence of infectious diseases is even devastating, leading to reduced survival rates, particularly in children and hampering the economy. The increase in pediatric population is one of the primary drivers for the global combination vaccines market. With the increase in pediatric population, the demand for combination vaccines for immunization has increased, as infants are more susceptible to various infectious diseases due to their weak immune systems. Occurrence of viral infections and diseases such as polio, tetanus, diphtheria, smallpox, chickenpox, and measles has been observed to be high among children in developing countries. This is anticipated to drive the demand for combination vaccines during the forecast period. As scientists are developing and testing new vaccines to protect children from more diseases, more combination vaccines may become available in the near future. This would allow children to get additional protection with a fewer number of shots.


The global combination vaccines market can be segmented into five major regions: North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. Asia Pacific is projected to register a high CAGR during the forecast period, due to rising pediatric population and increasing awareness about vaccination in the region. Continuous efforts by market players and national organizations to promote the use of combination vaccines would drive the market in developed countries in the near future.


Key players operating in the global combination vaccines market include GlaxoSmithKline, Merck & Co., Inc., Sanofi Aventis, Pfizer, Inc., Novartis AG, and Takeda Pharmaceutical Company Limited.

Remicade Biosimilar Market Competitive Analysis 2017 - 2025

Demand for biological products is high for the treatment of a large number of diseases. However, demand for biosimilar products is increasing to lower health care costs. Biosimilar products are derived in reference to biological products and have similar safety, efficacy, purity, and effectiveness when compared to the original products. Biosimilar can be characterized as a sort of biologic item that is profoundly like an as of now FDA approved biologic drug, known as reference drug. Biosimilars are drugs approved by the U.S. FDA and the European Medicine Agency (EMA) and show no clinical and meaningful difference from the reference biological product. These biosimilar products can be approved only for indications which are previously approved for the reference biological product by authorized regulatory bodies.


In 1998, the U.S. FDA licensed Remicade (infliximab), a monoclonal antibody originally produced by Janssen Biotech, Inc. and Merck & Co. in partnership. Its primary indication included Crohn’s disease in both adult and pediatric patients. It is also indicated for the treatment of ulcerative colitis, spinal psoriatic arthritis, plague psoriasis, and rheumatic arthritis when given in combination with methotrexate. The U.S. FDA approved biosimilar to Remicade named Inflectra on April 05, 2016. Pfizer launched Inflectra in the market at 15% discount on the original market price of the reference product. However, in April 2017, another biosimilar Renflexis (infliximab-abda), a tumor necrosis factor to Remicade by Samsung Bioepis and Merck & Co., was approved to be launched into the market. It is approved for almost all the indications that were approved under Remicade such as ulcerative colitis, spinal psoriatic arthritis, plague psoriasis, rheumatic arthritis, and ankylosing spondylitis.


Increase in incidence of autoimmune disorders such as rheumatoid arthritis, and psoriasis, patent expiry of branded drugs, and rise in health care costs drive the Remicade biosimilar market. Additionally, faster entry of Biosimilars into the Europe market leads to cost reduction and faster medicines accessibility help to grow this market. However, serious side effects associated with the drug could lead to fatality. This factor restraints the market.

The global Remicade biosimilar market can be segmented based on approved indication and region. In terms of approved indication, the market can be categorized into ulcerative colitis, rheumatoid arthritis, psoriatic arthritis, plaque psoriasis, Crohn’s disease, and ankylosing spondylitis. Ulcerative colitis and rheumatoid arthritis show higher demand due to increase in number of cases of these diseases. Psoriasis also increase market demand owing to increase in the cases of autoimmune diseases. Based on region, the global Remicade biosimilar market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America dominates the market owing to high incidence of autoimmune diseases and increase in geriatric population. Europe is the second largest market for Remicade. Easy access to biosimilar medications in the region drives the market. India, southeast Asia, and China are emerging markets for biosimilar medicines because of changing lifestyle and increase in healthcare facilities in these regions.



Key players in the global Remicade biosimilar market comprise Alvogen, Napp Pharmaceuticals, Janssen Biotech, Inc., Merck &Co., Pfizer, Inc., Cell Trion, and Nippon Kayaku.

Therapeutic Drug Monitoring (TDM) Market Current Trends and Future Aspect Analysis 2025

Therapeutic drug monitoring (TDM) is the clinical practice of determining the concentration of a specific drug in a patient’s bloodstream at different intervals. Therapeutic drug monitoring (TDM) helps to sustain a constant volume of drug in bloodstream required to show therapeutic effects without toxic effects, thereby optimizing individual dosage regimens. Therapeutic drug monitoring (TDM) is generally not deployed for majority of drugs, rather it is used primarily for monitoring drugs with narrow therapeutic window, medicines for which required concentrations are challenging to monitor, drugs with marked pharmacokinetic variability, and drugs known to cause adverse effects. TDM begins with the initiation of medication, and involves determining a preliminary dosage regimen suitable for the clinical state and patient characteristics as age, body mass index, weight, organ function, and associated drug therapy. TDM serves in assessing the efficiency and safety of a medication when administered into the individual patient.


The therapeutic drug monitoring (TDM) market is anticipated to witness healthy growth during the forecast period, owing to steep rise in the demand for better healthcare for the growing urban population. Increased knowledge of pharmacogenetics and pharmacokinetics of drugs is inclining the clinicians towards therapeutic drug monitoring (TDM) of certain medications. Rapid increase in the prevalence of complex neurological diseases and cancer have fueled the demand for high end diagnostic methods such as genetic testing which in turn is anticipated to boost therapeutic drug monitoring (TDM) market. Moreover, increasing investments in research and development of novel drugs and vaccines by private and government bodies is also expected to propel the demand for the therapeutic drug monitoring (TDM) market in the near future. In addition, rise in the geriatric population, especially in developing geographies and development of innovative tools in medication management are further driving this market. However, low research and development (R&D) returns, high infrastructure cost, stringent regulatory framework, and lack of trained resources are some of the restraints of the therapeutic drug monitoring (TDM) market.


The therapeutic drug monitoring (TDM) market can be segmented on the basis of product type, technology, drug class, end user and region. The product type segment can be further segmented into number of equipment such as immunoassay analyzers, spectrophotometers, chromatograms, and consumables. Increasing preference for technologically advanced services, product innovation, and growing number of diseases is anticipated to fuel the therapeutic drug monitoring (TDM) market growth. On the basis of technology the market is segmented into immunoassays such as chemiluminescent assays (CLIA), enzyme-linked immunosorbent assay (ELISA), proteomics technologies, chromatography, etc. On the basis of drug class, the market can be segmented into antiepileptics, antibiotics, psychoactive drugs, antiarrhythmic drugs, bronchodilators, immunosuppressants, and others.

Geographically, the therapeutic drug monitoring (TDM) market can be segmented into North America, Europe, Asia Pacific, Middle East and Africa and Latin America. North America is estimated to hold the largest share of the global therapeutic drug monitoring (TDM) market due to the presence of superior health care base, strong regional economics, and greater emphasis on prevention and wellness by government. This trend is also reflected in other countries. The therapeutic drug monitoring (TDM) market in Europe is expected to witness rapid growth, attributed to high consciousness about wellbeing in the region coupled with increasing spending on healthcare services. Countries such as China, Japan, and India in the Asia Pacific are poised to be the most promising markets for therapeutic drug monitoring (TDM) in the near future. Major factors for the positive outlook are extensive development of health care infrastructure, and growing emphasis on research and development in the health care sector.



Key players operating in the therapeutic drug monitoring market include Abbott Diagnostics, Danaher Corporation, F. Hoffmann-La Roche AG, Bio-Rad Laboratories Inc., Siemens Healthcare, Roche Diagnostics, Thermo Fisher Scientific, and Agilent Technologies.

Androgens and Anabolic Steroids Market Key Manufacturers, Development Trends And Competitive Analysis 2025

The male sex hormone androgens and anabolic steroids include di-hydro-testosterone, testosterone, and other agents. Androgen and anabolic steroid stimulate the development of male sex organs and male sexual characters such as growth of beard and deepening of voice. Various types of tissues grow due to stimulation of anabolic steroids, especially muscle and bone. Rise in red blood cells production is due to anabolic effects. Androgens and anabolic steroids are used for the treatment of breast cancer in women, impotence, hypogonadism in men, and replacement therapy for delayed puberty in adolescent boys. Androgens and anabolic steroids are also used for the treatment of various conditions with hormonal imbalance, weight loss, osteoporosis, and anemia.


Hypogonadism in men is caused by deficiency of androgen that adversely affects quality of life and multiple organ functions. Impotence is when men are unable to get erection. Impotence in men is primarily caused due to tiredness, lack of sleep, anxiety, and excessive intake of alcohol. Breast cancer in women is uncontrollable growth of the cells in the breast. These cells form tumor that can be felt as a lump or can often be seen on an X-ray. If these cells invade surrounding tissues, it is termed as malignant cancer.

Increase in geriatric population drives the androgens and anabolic steroids market, as older men are more prone to hypogonadism. Additionally, rise in obesity in men propels the global androgens and anabolic steroids market. The increasing poor health status especially in the developing countries is projected to fuel the growth of the market during the forecast period. Moreover, rise in government initiatives for better health care is attributed to the growth of the global androgens and anabolic steroids market. Increase in prevalence of hypogonadism among men is anticipated to augment the global androgens and anabolic steroids market during the forecast period. Rise in impotence among men due to obesity and tiredness is expected to boost demand for androgens and anabolic steroids during the forecast period.


The global androgens and anabolic steroids market can be segmented based on dosage form, disease type, end-user, and region. In terms of dosage form, the market can be categorized into oral/buccal, intranasal sprays, implantable pellets, transdermal patches and gels, and intramuscular injections. Based on disease type, the global androgens and anabolic steroids market can be divided into breast cancer in women, impotence, hypogonadism in men, and delayed puberty in adolescent boys. In terms of end-user, the market can be classified into online pharmacies, retail pharmacies, and online pharmacies. The hospital pharmacies segment dominated the market in 2016, owing to increased availability of drugs and hospitals being the first point of contact for treatment.

Geographically, the global androgens and anabolic steroids market can be segmented into Latin America, Asia Pacific, Europe, North America, and Middle East & Africa. North America held the largest market share in 2016, due to increased prevalence of breast cancer in women. According to many researches, breast cancer is one of the leading causes of death in the U.S. Europe held the second largest market share in 2016, due to increased prevalence of hypogonadism in men and delayed puberty in adolescent boys. The market in Asia Pacific is anticipated to grow at a rapid pace during the forecast period owing to increased government initiatives to eradicate breast cancer. The global androgens and anabolic steroids market in Middle East & Africa is expected to be driven by increased prevalence of impotence, hypogonadism in men, and delayed puberty in adolescent boys. The market in Latin America is projected to witness strong growth during the forecast period due to increased government initiatives in the health care sector.



Key players in the global androgens and anabolic steroids market include Unimed Pharmaceuticals, Inc. and Valeant Pharmaceuticals North America LLC.

Ocular Inserts Market – Latest Trends and Future Growth Study by 2025

Global Ocular Inserts Market: Overview

The demand for ocular inserts increased considerably in the past few years due to increasing incidences of glaucoma and other eye diseases. Application of ocular inserts seems a huge advancement in eye therapy.  Ease of administration by nurse and patients and continual release of medication into eyes are few advantages of using ocular inserts.

End-users and solubility of ocular inserts are the two major categories in which the global ocular inserts market is bifurcated. Bio-erodible ocular inserts, insoluble ocular inserts, and soluble ocular inserts are the key segments under the solubility category. Of these, insoluble ocular inserts are likely to hold a larger share in the market over the projected period.


The report contains detailed information on ocular inserts derived from primary and secondary research. Information is presented in a comprehensive manner that helps the readers to understand it more clearly and in a simple manner. It is gathered from various different sources but authentic sources such as government websites, international and national platforms, webinars, podcasts, and similar other sources. The emphasis is put on the key trends and opportunities created in the market and is divided into different segments.

Global Ocular Inserts Market: Trends and Opportunities

As per the data presented by the American Academy of Ophthalmology, more than 2.7 million people in the U.S. suffer from glaucoma. These people are generally above the age of 40 years. Apart from glaucoma, increasing cases of retinal vascular diseases has also come into notice that in turn boosted the demand in the global ocular inserts market. As ocular inserts help in easy delivery of drugs, its applications have increased considerably in eye therapy.

Extensive research and development taking place in the healthcare sector with an objective to develop innovative products to overcome complication in ocular treatment will benefit the growth of this market. In addition, faster clinical approvals from the government are expected to fuel demand in this market. Increasing bioavailability of newer drug delivery approach with a controlled dosage system is another crucial factor accelerating demand in the global ocular inserts market.


On the other hand, limited information about the drug delivery systems and awareness about ophthalmic disorders especially in developing economies might hamper the growth of ocular inserts.

Global Ocular Inserts Market: Geographic Analysis

On the account of rising incidence glaucoma and other chronic diseases, North America dominates the global ocular inserts market. High healthcare expenditure, high disposable income among the people, and spreading knowledge about the benefits of using ocular drug delivery systems have further strengthened the dominance of this market. The rising number of elderly in developed regions also augments the demand for ocular inserts. The report has also covered few other regions including Europe, Asia Pacific, the Middle East and Africa, and Latin America.

Among the developing regions, Asia Pacific shows growth at a significant rate in the global ocular inserts market. High investments made by governments in expanding the healthcare infrastructure and initiatives taken by them to provide better health facilities to the people who are blind. In addition, increasing incidence of glaucoma and increasing childhood blindness increased the demand for ocular inserts.


Global Ocular Inserts Market: Competitive Landscape


The report also includes a detailed analysis of the vendors operating in this market. It contains details about the key players and strategies used by these players. It stresses the key tools used by the vendors in order to gain a larger share in the market. Mergers and acquisition, expansion, collaboration, and partnership are the major strategic tools used by the vendors. Cost-effectiveness, expansion, product improvement, and innovations are largely integrated by prominent vendors. The researchers have analyzed few prominent players including Novartis AG, Ocular Therapeutix, Inc, EyeGate, Bausch & Lomb Incorporated, and few others.

Sacral Nerve Stimulation Market : Size, Application Analysis, Regional Outlook, 2017 - 2025

Global Sacral Nerve Stimulation Market: Overview

Sacral nerve stimulation (SNS), also known as sacral neuromodulation, is a medical electric stimulation therapy. It involves subcutaneous implantation of programmable stimulator. Several studies have been performed using electric stimulation therapy to treat patients with urinary problems, fecal incontinence, among others. The U.S. Food and Drug Administration approved sacral nerve stimulation therapy for the treatment of fecal incontinence in March 2011. The exact mechanism of sacral nerve stimulation therapy involves contraction of pelvic muscle and sphincter, which causes bladder contraction that involuntarily releases urine. Contraindications of sacral nerve stimulation involves diathermy use and mechanical outlet obstruction. Safety and efficacy of sacral nerve stimulation have not been determined in cases such as bilateral stimulation, pregnant patents, fetus, delivery, etc. Different types of sacral nerve stimulation available include external devices and implantable sacral nerve stimulation devices.


Sacral nerve stimulation is performed in two phases: evaluation phase and implant phase. Rise in chronic urinary diseases, increase in investment in research related activities, and technological advancements in the pharmaceutical & medical devices industry are anticipated to drive the global sacral nerve stimulation market during the forecast period. However, cost of sacral nerve stimulation devices is likely to restrain the global sacral nerve stimulation market. In 2016, Axonics Modulation Technologies announced the first in class rechargeable sacral nerve stimulation devices to manage fecal incontinence. Medtronic offers Interstim system is used to manage bladder and bowel control. As per InterStim sales analysis, more than 225,000 patients worldwide received sacral nerve stimulation for bladder and bowel control.


Global Sacral Nerve Stimulation Market: Key Segments

The global sacral nerve stimulation market is segmented based on type of nerve stimulation device, application, end-user, and geography. In terms of type of nerve stimulation device, the market is divided in implantable SNS device and external SNS device. Based on application, the sacral nerve stimulation market is categorized into urine incontinence, fecal incontinence, and other applications. In terms of end-user, the sacral nerve stimulation market is categorized into hospitals, ambulatory surgery centers, and others. Medtronic offered Interstim system includes lead placed parallel to sacral nerve, implantable neurostimulator, and patient programmer. Patient programmer is primarily used to set parameters of electric pulses. Education and awareness programs to make deeper adoption of sacral nerve stimulation technology is an imperative factor which is expected to boost the sacral nerve stimulation market during the forecast period.

Based on geographic, the global sacral nerve stimulation market is segmented into five key regions: Asia Pacific, North America, Europe, Latin America, and Middle East & Africa. North America is expected to account for a major share of the global sacral nerve stimulation market due to developed health care infrastructure and rise in number of patients with bowel disorders. Europe accounts for the second largest share of the sacral nerve stimulation market. India, China, and Japan are the most developing countries in Asia Pacific. These countries are expected to fuel the global sacral nerve stimulation market.


Global Sacral Nerve Stimulation Market: Key Players

Major players operating in the global sacral nerve stimulation market include Medtronic Inc., Axonics Modulation Technologies, Inc., Cogentix Medical, and Nuvectra Corporation.

Additive Manufacturing Technologies Market : Precise Analysis on Business Overview, Product Scope And Ongoing Market Development 2025

Global Additive Manufacturing Technologies Market: Overview

Technological advances have become an integral part of reconstructive surgery. New developments in software, imaging modalities, additive manufacturing, and customization of implants are poised to revolutionize the field of reconstructive surgery. Digital 3D design data is used in additive manufacturing technologies process to build a component in layers with deposition of material. Additive manufacturing technologies uses material in powder form to build a product. Additive manufacturing technologies are useful in cases where conventional technologies have limitations and when a new approach to design and manufacture is required to derive a solution. Additive technologies use a design driven manufacturing process, thereby enabling highly complex structures to be light and stable. The principle behind additive manufacturing technologies is applying a powder material in the form of layers to build the platform. Then a beam of powerful laser fuses with the powder exactly at defined points generated by computer component design data. Later the platform is lowered and the process is repeated for application of one more powder layer. There is again fusion of material and the technique used depending upon the type of material materials. Additive technology is effective in making pieces that are resilient and precise. Hence, the technology is being used to develop products with benefits such as design free, low quantity economic, material efficiency, predictable time, and reduced assembly space.


Global Additive Manufacturing Technologies Market: Drivers and Restraints

Rapidly changing economies of scale, rise in gold prices, outsourced manufacturing making it important to find cost effective methods, increase in demand for restoration, government investment, increased application areas, robust product development at low cost, and ease of development with customized products drive the global market. However, regulatory uncertainty, limited choice of materials used, material and process manufacturing qualification and certification standards, and ethical consideration are likely to restrain the market.


Global Additive Manufacturing Technologies Market: Key Segments
The global additive manufacturing technologies market can be segmented based on technology, processes, application, end-user, and region. In terms of technology, the additive manufacturing technologies market can be bifurcated into stereo lithography and 3D printing. Based on process, the global additive manufacturing technologies market can be classified into VAT photopolymerization, material jetting, material extrusion, binder jetting, sheet lamination, power bed fusion, and directed energy deposition. In terms of application, the additive manufacturing technologies market can be categorized into bone transplants, dentistry, plastic surgery, and artificial blood vessels. Based on end-user, the global additive manufacturing technologies market can be divided into high-end hospitals, dental clinics, ambulatory surgical centers, and medical research laboratories. In terms of region, the global additive manufacturing technologies market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa.

Several industrial applications for additive manufacturing technologies have been developed in the last five years. North America and Europe lead the global additive manufacturing technologies market. However, Asia Pacific is an attractive emerging additive manufacturing technologies market and is expected to lead the global additive manufacturing technologies market in the next few years. China and Japan are the leading additive manufacturing technologies market in Asia Pacific. The additive manufacturing technologies market is expected to expand in developing countries such as India and Brazil. Research and development activities mostly take place in the U.S., the U.K. and Germany. Several manufacturing firms are looking for investment in additive manufacturing technologies equipment in Latin America to expand in this potential market.


Global Additive Manufacturing Technologies Market: Key Players


Top players in the global additive manufacturing technologies market are 3D Systems, Arcam, Bespoke Innovations, Envision TEC, EOS, Innovation MediTech, Lima Corporate, Medial Modeling, Renishaw plc, Optomec, Organovo, Ossis, Oxford Performance Materials, and Visualization Sciences, among others.

Angiotensin Converting Enzyme Inhibitors Market : Trends Research and Projections for 2017 – 2025

Angiotensin converting enzyme inhibitors are a group of drugs used for the treatment of heart failure, high blood pressure (hypertension), or decrease complications of myocardial infarction (heart attack). These drugs are also useful in slowing down kidney disease progression in patients with chronic kidney disease or kidney disease in diabetic patients. The mechanism of action of angiotensin converting enzyme inhibitors is to decrease the amount of angiotensin II produced. Angiotensin II has an effect on the body to increase pressure in the kidney, blood volume, and blood pressure.


Angiotensin converting enzyme inhibitors widen the blood vessels by lowering the amount of angiotensin II in the body. These also increase the amount of urine produced by kidneys. This results in lowering of pressure in the kidney, lowering blood volume, and blood pressure. There is a drop in aldosterone and noradrenalin levels due to inhibition of angiotensin II by angiotensin converting enzyme inhibitors which helps in reducing blood pressure. Angiotensin converting enzyme inhibitors also increases bradykinin which widens the blood vessels, thereby decreasing blood pressure. These also cause a few side effects depending upon which type of angiotensin converting enzyme inhibitors are taken. Side effects include swelling of face or airways (angioedema), reduced kidney function, dizziness, high potassium levels (hyperkalemia), dry cough, and low blood pressure (hypotension).
Increase in prevalence of high blood pressure is the major factor driving the angiotensin converting enzyme inhibitors market. According to the World Health Organization, over 1 in 5 adults suffer from high blood pressure globally. Complications of high blood pressure cause approximately 9.4 million deaths across the world each year. Rise in prevalence of heart failure also propels the angiotensin converting enzyme inhibitors market. According to the Centers for Disease Control and Prevention (CDC), approximately 5.7 million adults in the U.S. suffer from heart failure each year, nearly half of these people die within five years of diagnosis.


The global angiotensin converting enzyme inhibitors market can be segmented based on disease type, dosage form, and distribution channel. In terms of disease type, the Angiotensin Converting Enzyme Inhibitors market can be divided into heart failure, high blood pressure (hypertension), heart attack, and kidney disease. Based on dosage form, the global angiotensin converting enzyme inhibitors market can be categorized into oral tablets and oral solution. Based on distribution channel, the angiotensin converting enzyme inhibitors market can be classified into online pharmacies, retail pharmacies, and hospital pharmacies.

Geographically, the global angiotensin converting enzyme inhibitors market can be segmented into Latin America, Asia Pacific, Europe, North America, and Middle East & Africa. North America held the largest angiotensin converting enzyme inhibitors market share in 2016. Rise in prevalence of heart failure, heart attack, and high blood pressure drive the angiotensin converting enzyme inhibitors market in the region. Europe held the second largest market share in 2016. Increase in prevalence of kidney disease and high blood pressure in the region fuel the growth of the market in the region. The angiotensin converting enzyme inhibitors market in Asia Pacific is anticipated to be driven by increase in government initiatives for the health care sector especially in countries such as India and China. The global angiotensin converting enzyme inhibitors market in Middle East & Africa is anticipated to be driven by initiatives taken by the governments in the health care sector. The angiotensin converting enzyme inhibitors market in Latin America is anticipated to experience strong growth during the forecast period owing to the government initiatives for heart diseases in the region.



Key players in the global angiotensin converting enzyme inhibitors market include Bristol-Myers Squibb Company, Par Pharmaceutical Companies, Inc., UCB, Inc., Pfizer, Inc., and AstraZeneca.

Swine Flu Drugs Market Boosting the Healthcare Industry Worldwide

Global Swine Flu Drugs Market: Overview

The swine flu drugs market is expected to grow significantly in the coming years, as number of people suffering from swine flu has increased largely in the past few years. People who have weak immune system, diabetic patients, and people with heart problems, besides children and pregnant women have high risk of getting swine flu.

The global swine flu drugs market can be classified on the basis of dosage from, drug class, and distribution channel. On the basis of distribution channel, the market is segmented into retail pharmacies, online pharmacies, and hospital pharmacies. In 2016, the hospital pharmacies segment held maximum share due to wide availability of swine flu drugs in them. Based on dosage form, the market can be classified into oral powder inhalation and capsule.

The report on the global swine flu drugs market presents an in-depth analysis on this market. It includes the major factors responsible for the growth of this market. Drivers and restraints give the current picture of the market, whereas trends and opportunities will provide how the demand for intelligent apps will shape in future. Segmentation supports and justifies the above-mentioned factors. In addition, geographic analysis and vendor landscape explains how investors and players can take strategic decisions in the coming years.


Global Swine Flu Drugs Market: Trends and Opportunities

Swine flu is caused by a strain of the influenza type a virus known as H1N1. The first outbreak of this type of virus was seen in 1930 in the United States where people were closely associated with pigs. In 2009, outbreak of swine flu was seen in Mexico that affected humans at a large scale. Currently, vaccination and antiviral drugs are used to treat influenza. Researchers are making efforts to improve methods of vaccine production that will make it quicker and more affordable. Moreover, two favorable novel peramivir, NA inhibitors, and laninamivir are being evaluated in phase III clinical trials. Thus, benefitting the swine flu drugs market.

Global Swine Flu Drugs Market: Geographic Analysis

Key regions covered in the report on the swine flu drugs market include Asia Pacific, Latin America, North America, Europe, and Middle East & Africa. Of these regions, Asia Pacific is expected to lead the market as it held dominate share in 2016. Rising prevalence of swine flu in the region is the major factor for the dominance of this region.  Europe and North America held significant share in 2016.  Rising prevalence of infectious diseases in Europe among people having long-term health conditions, pregnant women, young children, and elderly is expected to drive the demand in this market.


Global Swine Flu Drugs Market: Competitive Landscape


The competitive landscape presents key players functioning in the global swine flu drugs market. Gilead Sciences, Inc., F. Hoffmann-La Roche AG, Genentech, Inc., BioCryst Pharmaceuticals, Inc., and GlaxoSmithKline are some of the key players. Leading players in the market are likely to use advanced business development strategies. This will help them to form a firm hold in the market and expand their business in different geographies.